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GPCR/G Protein
Metabotropic glutamate receptors (mGluR)

Metabotropic glutamate receptors (mGluR)

Catalog No.

Product Name

Application

Product Information

Product Citation

A11487

LY2979165

mGlu2 agonist

LY2979165 is a mGlu2 agonist.

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A12909

JNJ-40411813

mGluR2 PAM

JNJ-40411813 is a novel mGluR2 PAM.

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A19689

VU0650786

CNS penetrant modulator

VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM), with an IC50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents.

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A19729

AZD 2066

mGluR5 antagonist

AZD 2066 is a selective, orally active and brain-penetrant mGluR5 antagonist, with analgesia activity.

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