Neurotensin Receptors

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  1. NTR1 allosteric modulator

    SBI-553 is a potent and brain penetrant NTR1 allosteric modulator.
  2. NK2 receptor peptide antagonist

    GR 64349 is a potent and highly selective NK2 receptor peptide antagonist, with an EC50 of 3.7 nM in rat colon. GR 64349 exhibits selectivity >1000 and >300-fold with respect to NK1 and NK3 receptors, respectively.

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