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CXCR

Catalog No.

Product Name

Application

Product Information

Product Citation

A19953

ML 145

GPR35/CXCR8 antagonist

ML 145 is a selective GPR35/CXCR8 antagonist with an IC50/EC50 of 20.1 nM, but not for the related GPR55 orphan receptor. GPR35 is expressed by various cells of the immune system and it may has potential as a therapeutic target in inflammatory disease.

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A21874

AMG 487 S-enantiomer

CXCR3 antagonist

AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an antagonist of the chemokine receptor CXCR3.

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