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Publications citing Adooq Products
Chemical Information
| Catalog Num | A10184 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 497.0 |
| Formula | C23H25ClN8OS |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 942947-93-5 |
| Synonyms | CCT-129202 |
| SMILES | CN(C)C1=CC=C(C=C1)C2=NC3=NC=C(C(=C3N2)N4CCN(CC4)CC(=O)NC5=NC=CS5)Cl |
Description |
CCT129202 is a representative of a structurally novel series of imidazopyridine small-molecule inhibitors of Aurora kinase activity. It shows high selectivity for the Aurora kinases over a panel of other kinases tested and inhibits proliferation in multiple cultured human tumor cell lines. |
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Targets |
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| Solubility (25°C) * | In vitro | DMSO | 3 mg/mL (6.03 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
| In vivo | 1% DMSO/30% polyethylene glycol/1% Tween 80 | 30 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.12 mL | 100.6 mL | 201.21mL |
| 0.5 mM | 4.02 mL | 20.12 mL | 40.24 mL |
| 1 mM | 2.01 mL | 10.06 mL | 20.12 mL |
| 5 mM | 0.4 mL | 2.01 mL | 4.02 mL |
*The above data is based on the productmolecular weight 497.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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