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CDK9 degrader PROTAC
THAL-SNS-032 is a selective CDK9 degrader PROTAC consisting of a CDK-binding SNS-032 ligand linked to a thalidomide derivative that binds the E3 ubiquitin ligase Cereblon (CRBN). -
CDK6 degrader
BSJ-03-123 is a potent and novel CDK6-selective small-molecule degrader (PROTAC).