DYRK

Mirk-IN-1 is a potent inhibitor of Dyrk1B(Mirk kianse) and Dyrk1A with IC50 of 68??48 nM and 22??8 nM respectively.

tBID is a selective inhibitor of homeodomain-interacting protein kinase 2 (HIPK2) with an IC50 of ?0.33 ?M.

GSK-626616 is a potent, orally bioavailable inhibitor of DYRK3 (IC50=0.7 nM).