Metabolism

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Catalog No.
Product Name
Application
Product Information
Product Citation
  1. PP2A inhibitor

    LB-100 is a small-molecular protein phosphatase 2A(PP2A)inhibitor with IC50 of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.
  2. IMPase inhibitor

    L-690330 is a competitive inhibitor of inositol monophosphatase (IMPase) with Kis of 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase, respectively.
  3. protein phosphatase inhibitor

    Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1.
  4. serine/threonine phosphatase inhibitor

    Fumonisin B1 is a fungal metabolite produced by Fusarium moniliforme, that has been shown to inhibit protein serine/threonine phosphatases (PP1, PP2A, PP2B, PP2C, and PP5/T/K/H), and is most effective with PP5.
  5. SHIP2 inhibitor

    CPDA is a novel potent SHIP2 inhibitor that can effectively ameliorate insulin resistance in 3T3-L1 adipocytes.
  6. PHLPP inhibitor

    NSC117079 is a novel pan-PHLPP inhibitors (selective for PHLPP1 and PHLPP2).
  7. DUSP26 inhibitor

    F1063-0967 is a novel inhibitor of dual-specificity phosphatase 26 (DUSP26), inducing apoptosis in IMR-32 cell line.
  8. TNAP inhibitor

    SBI-425 is a potent, selective and oral bioavailable tissue-nonspecific alkaline phosphatase (TNAP) inhibitor.
  9. CDC25 phosphatase family inhibitor

    BN82002 is a potent, selective and irreversible inhibitor of CDC25 phosphatase family.
  10. ecto-ATPase inhibitor

    ARL67156 trisodium salt is an inhibitor of ecto-ATPase. ARL 67156 is a weak competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12?μM, respectively.
  11. LYP inhibitor

    LTV-1 is a highly potent, cell-permeable and reversible inhibitor of lymphoid tyrosine phosphatase (LYP) (IC50 = 508 nM).
  12. DDHD2 inhibitor

    KLH45 is a potent and selective DDHD2 inhibitor, with an IC50 of 1.3 nM.

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