Metabolism

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  1. C5a receptor antagonist

    PMX-205 is a cyclic hexapeptide that acts as a potent antagonist of C5a receptor (C5aR; IC50 = 31 nM).
  2. C3a receptor antagonist

    SB290157 trifluoroacetate is a potent and selective C3a receptor antagonist with an IC50 of 200 nM.

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