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Liver X Receptor Agonist
GW3965 is a potent, selective LXR agonist for hLXRα and hLXRβ with EC50 of 190 and 30 nM, respectively.- B Dong ,etc. High-fructose diet downregulates long-chain acyl-CoA synthetase 3 expression in liver of hamsters via impairing LXR/RXR signaling pathway. Journal of lipid research, 2013, 54(5), 1241-1254.
- N Pencheva ,etc. Broad-spectrum therapeutic suppression of metastatic melanoma through nuclear hormone receptor activation. Cell, 2014, 156(5), 986-1001.
