Oxidative Phosphorylation (OXPHOS)

Imeglimin is the first in a new tetrahydrotriazine-containing class of oral antidiabetic agents, the glimins. It has been shown to act on the liver, muscle and pancreatic ??-cells to uniquely target the key defects of type 2 diabetes.

FCCP is an ionophore that is a mobile ion carrier. It is a potent uncoupler of oxidative phosphorylation in mitochondria that disrupts ATP synthesis by transporting protons across cell membranes.

Oxyclozanide is a salicylanilide anthelmintic that is a proton ionophore which uncouples oxidative phosphorylation of the target organism.

Acetomenaphthone is synthetic vitamin K which is also known as vitmin K4

Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations.

VLX600 is an iron-chelating inhibitor of oxidative phosphorylation (OXPHOS).