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Metabolism
Phospholipases

Phospholipases

Catalog No.

Product Name

Application

Product Information

Product Citation

A11566

SPK-601

PC-PLC inhibitor

SPK-601 (LMV-601) is an inhibitor of the phosphatidylcholine-specific phospholipase C (PC-PLC). SPK-601 also can be used as an antimicrobial agent.

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A12301

ML349

APT-2 inhibitor

ML349 is a potent and specific acyl protein thioesterase 2 (APT-2) inhibitor with a Ki of 120 nM. ML349 is also an inhibitor of LYPLA2 with an IC50 of 144 nM.

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A13229

Rilapladib

Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) inhibitor

Rilapladib is a selective Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) inhibitor with an IC50 of 230 pM.

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A22089

ML298

Phospholipase D2 (PLD2) inhibitor

ML298 (CID53393915) is a potent, specific inhibitor of Phospholipase D2 (PLD2) with IC50 of 355 nM.

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A22091

YM26734

rabbit platelet sPLA2 inhibitor

YM-26734 is a rabbit platelet sPLA2 inhibitor that has been used to ameliorate local inflammatory responses in TPA-induced mouse ear edema.

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