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TTK inhibitor
CFI-402257, a pyrazolopyridin derivative, has been found to be a TTK inhibitor that could influence chromosome segregation and induce cell death so that is significant in anticancer studies.- Jian Yu, .et al. , BMC Cancer, 2022, Jul 18;22(1):786 PMID: 35850753
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Mps1 inhibitor
Empesertib (BAY 1161909) is a potent Mps1 inhibitor, with an IC50 of < 1 nM.
