- Inês GARCEZ PALHA, .et al. An in vivo translation-reporter system for the study of protein synthesis in zebrafish embryos, Biol Open, 2018, Nov 7 PMID: 30404898
- Hui Shen, .et al. Inhibitory Effects of Caffeic Acid Phenethyl Ester Derivatives on Replication of Hepatitis C Virus, PLoS One., 2013, 8(12): e82299 PMID: 24358168
Biological Activity
Danoprevir is a potent inhibitor of the HCV NS3/4A serine protease.
Targets
HCV NS3/4A protease | ||||
0.2 nM-3.5 nM |
In vitro | DMSO | 124 mg/mL (169.43 mM) | |
Water | Insoluble | ||
Ethanol | 124 mg/mL (169.43 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 13.66 mL | 68.32 mL | 136.65 mL |
0.5 mM | 2.73 mL | 13.66 mL | 27.33 mL |
1 mM | 1.37 mL | 6.83 mL | 13.66 mL |
5 mM | 0.27 mL | 1.37 mL | 2.73 mL |
*The above data is based on the productmolecular weight 731.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10284 |
---|---|
Actions | Inhibitor |
CAS No. | 850876-88-9 |
Formula | C35H46FN5O9S |
M. Wt | 731.8 |
Purity | >98% |
Synonyms | RG7227, ITMN-191, RO5190591 |
SMILES | CC(C)(C)OC(=O)N[[email protected]]1CCCCC/C=C\[[email protected]@H]2C[[email protected]]2(NC(=O)[[email protected]@H]3C[[email protected]](CN3C1=O)OC(=O)N4CC5=C(C4)C(=CC=C5)F)C(=O)NS(=O)(=O)C6CC6 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Datasheet
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