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Publications citing Adooq Products
Danoprevir (RG7227) Citations (2)
- Inês GARCEZ PALHA, .et al. An in vivo translation-reporter system for the study of protein synthesis in zebrafish embryos, Biol Open, 2018, Nov 7 PMID: 30404898
- Hui Shen, .et al. Inhibitory Effects of Caffeic Acid Phenethyl Ester Derivatives on Replication of Hepatitis C Virus, PLoS One., 2013, 8(12): e82299 PMID: 24358168
Chemical Information
| Catalog Num | A10284 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 717.9 |
| Formula | C35H48FN5O8S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 850876-88-9 |
| Synonyms | RG7227, ITMN-191, RO5190591 |
| SMILES | CC(C)(C)OC(=O)N[[email protected]H]1CCCCC/C=C/[[email protected]@H]2C[[email protected]]2(NC(=O)[[email protected]@H]3C[[email protected]](CN3C1=O)OC(=O)N4CC5=C(C4)C(=CC=C5)F)C(=O)NS(=O)(=O)C6CC6 |
Description |
Danoprevir is a potent inhibitor of the HCV NS3/4A serine protease. | ||||||||||
Targets |
|
||||||||||
| Solubility (25°C)* | In vitro | DMSO | 144 mg/mL (196.76 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 144 mg/mL (196.76 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 13.93 mL | 69.65 mL | 139.3mL |
| 0.5 mM | 2.79 mL | 13.93 mL | 27.86 mL |
| 1 mM | 1.39 mL | 6.96 mL | 13.93 mL |
| 5 mM | 0.28 mL | 1.39 mL | 2.79 mL |
*The above data is based on the productmolecular weight 717.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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