Total item
Cart Subtotal
$0.00 - Inês GARCEZ PALHA, .et al. An in vivo translation-reporter system for the study of protein synthesis in zebrafish embryos, Biol Open, 2018, Nov 7 PMID: 30404898
- Hui Shen, .et al. Inhibitory Effects of Caffeic Acid Phenethyl Ester Derivatives on Replication of Hepatitis C Virus, PLoS One., 2013, 8(12): e82299 PMID: 24358168
Biological Activity
Danoprevir is a potent inhibitor of the HCV NS3/4A serine protease.
Targets
| HCV NS3/4A protease | ||||
| 0.2 nM-3.5 nM |
| In vitro | DMSO | 144 mg/mL (196.76 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 144 mg/mL (196.76 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 13.93 mL | 69.65 mL | 139.3 mL |
| 0.5 mM | 2.79 mL | 13.93 mL | 27.86 mL |
| 1 mM | 1.39 mL | 6.96 mL | 13.93 mL |
| 5 mM | 0.28 mL | 1.39 mL | 2.79 mL |
*The above data is based on the productmolecular weight 717.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10284 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 717.9 |
| Formula | C35H48FN5O8S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 850876-88-9 |
| Synonyms | RG7227, ITMN-191, RO5190591 |
| SMILES | CC(C)(C)OC(=O)N[[email protected]]1CCCCC/C=C/[[email protected]@H]2C[[email protected]]2(NC(=O)[[email protected]@H]3C[[email protected]](CN3C1=O)OC(=O)N4CC5=C(C4)C(=CC=C5)F)C(=O)NS(=O)(=O)C6CC6 |
Datasheet
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
BMS-790052 (Daclatasvir)
BMS-790052 is an NS5A inhibitor under investigation for the treatment of hepatitis C virus (HCV) infection.
Balapiravir (R1626)
Balapiravir (R1626, RG1626) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R…
Asunaprevir (BMS-650032)
Asunaprevir is an inhibitor of the viral enzyme serine protease NS3.
VX-222
VX-222 is a small molecule non-nucleoside inhibitor of HCV NS5B polymerase that is being investigated for the treatment of hepatitis C virus…
Ciluprevir (BILN 2061)
Ciluprevir is a specific and potent peptidomimetic inhibitor of the HCV NS3 protease.
Boceprevir (SCH-503034)
Boceprevir is a protease inhibitor used as a treatment for hepatitis C genotype 1.
Telaprevir (VX-950)
Telaprevir (VX-950) is known as protease inhibitors that inhibits the hepatitis C virus NS3.4A serine protease.
Keywords:buy Danoprevir (RG7227) | Danoprevir (RG7227) Supplier | purchase | cost | manufacturer | order | distributor | buy 850876-88-9| 850876-88-9 Supplier | purchase 850876-88-9 | 850876-88-9 cost | 850876-88-9 manufacturer | order 850876-88-9 | 850876-88-9 distributor
Adooq Quality Guarantee
We promise all products perform as described.