PHA-767491 is a potent, ATP-competitive dual cdc7/cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication.
PHA-767491 is a potent, ATP-competitive dual cdc7/cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication.
Targets
Target
Value
Product Information
Catalog Num
A11164
Formula
C12H11N3O
Molecular Weight
213.24
CAS Number
845714-00-3
SMILES
C1CNC(=O)C2=C1NC(=C2)C3=CC=NC=C3
Synonyms
PHA767491
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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