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DNA Damage
Sirtuins

Sirtuins

Catalog No.

Product Name

Application

Product Information

Product Citation

A19026

SRT 1460

SIRT1 activator

SRT 1460, a potent Sirtuin-1 (SIRT1) activator with an EC1.5 value of 2.9 μM, shows good selectivity for activation of SIRT1 versus SIRT2 and SIRT3 (EC1.5>300 μM), and is more potent than Resveratrol and the closest sirtuin homologues.

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A20961

SIRT-IN-2

SIRT1/2/3 inhibitor

SIRT-IN-2 is a potent inhibitor of SIRT1/2/3, with IC50s of 4, 4, 7 μM, respectively.

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A20962

SIRT-IN-1

SIRT1/2/3 inhibitor

SIRT-IN-1 is a potent inhibitor of SIRT1/2/3, with IC50s of 15, 10, 33 μM, respectively.

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A22709

4'-bromo-Resveratrol

SIRT1/SIRT3 inhibitor

4'-bromo-Resveratrol is a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3).

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