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Catalog No.
Product Name
Application
Product Information
Product Citation
JMS-17-2 is a potent and selective CX3CR1 antagonist with an IC50 of 0.32 nM.
HGPR91 antagonist 1 is a potent and selective small molecule hGPR91 antagonist with an IC50 of 7 μM.
Firuglipel (DS-8500a) is an orally available, potent and selective GPR119 agonist.
brain-penetrant GPR88 agonist
RTI-13951-33 is a potent, selective, and brain-penetrant GPR88 agonist, with an EC50 of 25 nM in GPR88 cAMP functional assay.
ML 145 is a selective GPR35/CXCR8 antagonist with an IC50/EC50 of 20.1 nM, but not for the related GPR55 orphan receptor. GPR35 is expressed by various cells of the immune system and it may has potential as a therapeutic target in inflammatory disease.
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