Protein Arginine Deiminase (PAD)

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  1. PAD inhibitor

    Cl-amidine is a peptidylarginine deminase (PAD) inhibitor, with an IC50 5.9 μM for PAD4.
  2. PAD4 inhibitor

    GSK484 hydrochloride (GTPL8577) is a selective and reversible peptidylarginine deiminase 4 (PAD4) inhibitor.
  3. pan-PAD inhibitor

    Streptonigrin (Bruneomycin), a natural product produced by Streptomyces flocculus, possesses both anti-tumor and anti-bacterial activity. Streptonigrin acts as a pan-PAD inhibitor with IC50s of 48.3??34.2 ?M, 26.1??0.3 ?M, 0.43??0.03 ?M, and 2.5??0.4 ?M for PAD1, PAD2, PAD3, and PAD4, respectively.
  4. PAD inhibitor

    BB-Cl-Amidine is a peptidylarginine deminase (PAD) inhibitor.
  5. PAD inhibitor

    YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4.
  6. PAD inhibitor

    Cl-amidine (hydrochloride) is a peptidylarginine deminase (PAD) inhibitor, with an IC50 5.9 μM for PAD4.
  7. GSK106 is a negative control compound that can be used in binding and functional assays for PAD4 inhibitors.
  8. PAD4 inhibitor

    GSK121 trifluoroacetate is a selective inhibitor of PAD4.
  9. PAD4 inhibitor

    GSK199 is a selective inhibitor of PAD4 with IC50 of 200 nM in the absence of calcium.
  10. peptidylarginine deminase (PAD) inhibitor

    Cl-amidine TFA is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively.

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