Fosbretabulin disodium (CA4P)

Catalog No.: A13081

microtubule-targeting agent

Fosbretabulin disodium (CA4P)

Fosbretabulin disodium (CA4P) Chemical Structure

CAS NO. 168555-66-6, 222030-63-9

Fosbretabulin disodium is the disodium salt of a water-soluble phosphate derivative of a natural stilbenoid phenol derived from the African bush willow (Combretum caffrum) with potential vascular disrupting and antineoplastic activities.

Availability: In stock

Package Price Qty
10 mg
$63.00
25 mg
$126.00
50 mg
$300.00
100 mg
$430.00
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Biological Activity

Fosbretabulin disodium is the disodium salt of a water-soluble phosphate derivative of a natural stilbenoid phenol derived from the African bush willow (Combretum caffrum) with potential vascular disrupting and antineoplastic activities.
Targets
Tubulin (Cell-free assay)
2.4 μM
In vitro (25°C) DMSO Insoluble
Water 25 mg/mL (56.78 mM)
Ethanol Insoluble
In vivo Saline with a few drops of 5% Na2CO3 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.71 mL 113.56 mL 227.12 mL
0.5 mM 4.54 mL 22.71 mL 45.42 mL
1 mM 2.27 mL 11.36 mL 22.71 mL
5 mM 0.45 mL 2.27 mL 4.54 mL

*The above data is based on the productmolecular weight 440.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13081
CAS No. 168555-66-6, 222030-63-9
Formula C18H19Na2O8P
M. Wt 440.29
Purity >98%
SMILES COC1=C(C=C(C=C1)/C=C\C2=CC(=C(C(=C2)OC)OC)OC)OP(=O)([O-])[O-].[Na+].[Na+]
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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