Ibuprofen (Advil)

Catalog No.: A10461

COX-1 inhibitor

Ibuprofen (Advil) Chemical Structure

CAS NO. 15687-27-1

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) targeting COX-1 with an IC50 of 13 μM.

Availability: In stock

Package Price Qty
200 mg
$40.00
500 mg
$95.00
10mM * 1mL in DMSO
$59.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) targeting COX-1 with an IC50 of 13 μM.
Targets
COX-1 COX-2
13 μM370 μM
In vitro (25°C) DMSO 41 mg/mL (198.75 mM)
Water <1 mg/mL (<1 mM)
Ethanol 41 mg/mL (198.75 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 48.47 mL 242.37 mL 484.73 mL
0.5 mM 9.69 mL 48.47 mL 96.95 mL
1 mM 4.85 mL 24.24 mL 48.47 mL
5 mM 0.97 mL 4.85 mL 9.69 mL

*The above data is based on the productmolecular weight 206.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10461
Actions Inhibitor
M. Wt 206.3
Formula C13H18O2
Solubility No
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 15687-27-1
Synonyms Genpril, Brufen, Nurofen, Motrin, Ibren, Ibuprohm
SMILES CC(C)CC1=CC=C(C=C1)C(C)C(=O)O

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