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Ibuprofen (Advil)

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COX-1 inhibitor

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Catalog No. A10461

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Ibuprofen 200mg A10461-200

Regular Price: $40.00

Special Price: $36.00

Ibuprofen 500mg A10461-500

Regular Price: $95.00

Special Price: $85.50

Ibuprofen (Advil) 10mM * 1mL in DMSO A10461-10mM-D

Regular Price: $59.00

Special Price: $53.10

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) targeting COX-1 with an IC50 of 13 μM.

Ibuprofen (Advil)

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Publications citing Adooq Products
Ibuprofen (Advil) Citations (2)
  • Azuma T,et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 28660504
  • Azuma T,et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 26802347

Chemical Information

Catalog Num A10461
Actions Inhibitor
M. Wt 206.3
Formula C13H18O2
Solubility No
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 15687-27-1
Synonyms Genpril, Brufen, Nurofen, Motrin, Ibren, Ibuprohm
SMILES code CC(C)CC1=CC=C(C=C1)C(C)C(=O)O
Chemical Name (RS)-2-(4-(2-methylpropyl)phenyl)propanoic acid

Biological Activity

Description
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) targeting COX-1 with an IC50 of 13 μM.
Targets
COX-1 COX-2
13 μM370 μM

Solubility

Solubility (25°C) * In vitro DMSO 41 mg/mL (198.75 mM)
Water <1 mg/mL (<1 mM)
Ethanol 41 mg/mL (198.75 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 48.47 mL 242.37 mL 484.73mL
0.5 mM 9.69 mL 48.47 mL 96.95 mL
1 mM 4.85 mL 24.24 mL 48.47 mL
5 mM 0.97 mL 4.85 mL 9.69 mL

*The above data is based on the productmolecular weight 206.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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