Immunology & Inflammation

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  1. BMI-1 inhibitor

    PTC-209 HBr is the hydrobromide salt of PTC-209PTC-209 is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM in HEK293T cell line, and results in irreversible reduction of cancer-initiating cells (CICs).

  2. BMI-1 inhibitor

    PTC-028 is an orally bioavailable compound that decreases BMI-1 levels by posttranslational modification

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