Keap1-Nrf2

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  1. Nrf2 inhibitor

    RTA-408 is a synthetic triterpenoid that potently activates the antioxidative transcription factor Nrf2 and inhibits the proinflammatory transcription factor NF-kB.
  2. Nrf2 inhibitor

    Brusatol is a biochemical, isolated from the Brucea javanica plant, that inhibits Nrf2.
  3. KEAP1/NRF2 interaction inhibitor

    KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction. KI696 is a potent and selective inhibitor of the KEAP1/NRF2 interaction.

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