Toll-like Receptors

CU-CPT9b is a specific TLR8 antagonist, with an IC50 of 0.7 nM. CU-CPT9b shows high binding affinity towards TLR8 with a Kd of 21 nM.

CU-CPT-8m is a specific TLR8 antagonist, with an IC50 of 67 nM.