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- Clavulanic acid is a mechanism-based β-lactamase inhibitorcombined with penicillin group antibiotics to overcome certain types of antibiotic resistance.
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β-lactamase inhibitor
Zidebactam (WCK-5107) is a potent β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL.
