GABA Receptors

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  1. Piperazine Citrate is an organic compound that consists of a six-membered ring, containting two nitrogen atoms at opposite positions in the ring; first introduced in 1953 as an Anthelmintic.
  2. chemoprotective agent

    Methionine (MRX-1024; D-Methionine) is an effective chemoprotective agent which can also inhibit the neuronal activity through GABAA receptor activation.
  3. GABAA receptor inverse agonist

    L-655708 is a potent α5 subunit-selective GABAA receptor inverse agonist (Ki = 0.45 nM).
  4. GABAAα5 modulator

    Basmisanil is a highly selective GABAAα5 negative allosteric modulator.
  5. GABA(A) receptor modulator

    NS11394 is a potent and subtype-selective GABA(A) receptor-positive modulator; possesses a functional efficacy selectivity profile of alpha(5) > alpha(3) > alpha(2) > alpha(1) at GABA(A) alpha subunit-containing receptors.
  6. Benzodiazepine inverse agonist

    DMCM (hydrochloride) is Benzodiazepine inverse agonist that displays anxiogenic and potent convulsant activity.
  7. GABAB receptor positive allosteric modulator

    SSD114 hydrochloride is a novel GABAB receptor positive allosteric modulator.
  8. nervoussystem toxicant

    Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects.
  9. positive allosteric modulator of different isoforms of the GABAA receptor

    SJM-3 is a positive allosteric modulator of different isoforms of the GABAA receptor. SJM-3 binds at the high-affinity benzodiazepine binding site at the α+/γ- subunit interface.
  10. pyrazolopyridine anxiolytic

    Tracazolate is a pyrazolopyridine anxiolytic known to interact with gamma-aminobutyric acid (GABA)(A) receptors, adenosine receptors, and phosphodiesterases.

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