PF 429242

Name: PF 429242
Brand: Adooq Bioscience
SKU: A11230
Rating: 5 (9 reviews)

Catalog No.: A11230

SREBP inhibitor

Adooq's PF 429242 has been cited by 9 publications

PF 429242 is a reversible, competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease.

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Grouped product items
Size	Price	Stock
1mg	$30.00	In stock
2mg	$45.00	In stock
5mg	$55.00	In stock
10mg	$75.00	In stock
25mg	$175.00	In stock
50mg	$295.00	In stock
100mg	$545.00	In stock
*10mM 1mL in DMSO**	$95.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

Other Forms of PF 429242

PF429242 dihydrochloride

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Adooq Products cited in reputable paper

Adooq's PF 429242 has been cited by 9 publications

Ziqing Yan, .et al. , Am J Physiol Cell Physiol, 2024, Jun 1;326(6):C1683-C1696 PMID: 38646785
Kai Xue, .et al. , Oxid Med Cell Longev, 2021, Nov 26;2021:5710440 PMID: 34873430
Tong-bing Wang, .et al. , Cell Death Dis, 2021, Aug; 12(8): 717 PMID: 34285190
Shiying Xie, .et al. , Am J Physiol Renal Physiol, 2020, Aug 31 PMID: 32865015
Yang PM, .et al. , Am J Cancer Res, 2019, Oct 1;9(10):2120-2139 PMID: 31720078
Hui Fang, .et al. , Am J Physiol Cell Physiol, 2017, Dec 1; 313(6): C632-C643 PMID: 28903918
Tsutomu Nakagawa, .et al. , J Biochem, 2016, Apr 1;161(4):369-379 PMID: 28013223
Shimada S, .et al. , Virology, 2015, Aug;482:19-27 PMID: 25817401
Jan H. Reiling, .et al. , Nat Cell Biol., 2013, 15(12): 1473-1485 PMID: 24185178

Biological Activity

Description	PF 429242 is a reversible, competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease.

Product Information

Catalog Num	A11230
Formula	C25H35N3O2
Molecular Weight	409.56
CAS Number	947303-87-9
SMILES	CCN(CC)CC1=CC=C(C=C1)C(=O)N(CCC2=CC=CC=C2OC)[C@@H]3CCNC3
Synonyms	PF-429242, PF429242
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	77 mg/mL (188 mM)
	* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.42 mL	122.08 mL	244.16 mL
0.5 mM	4.88 mL	24.42 mL	48.83 mL
1 mM	2.44 mL	12.21 mL	24.42 mL
5 mM	0.49 mL	2.44 mL	4.88 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂