PF 429242

Catalog No.: A11230
SREBP inhibitor
PF 429242 is a reversible, competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease.
Grouped product items
Product Name Price Stock Qty
PF 429242 10mg
$80.00
In stock
PF 429242 25mg
$180.00
In stock
PF 429242 50mg
$300.00
In stock
PF 429242 100mg
$550.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's PF 429242 has been cited by 8 publications
  • Kai Xue, .et al. , Oxid Med Cell Longev, 2021, Nov 26;2021:5710440 PMID: 34873430
  • Tong-bing Wang, .et al. , Cell Death Dis, 2021, Aug; 12(8): 717 PMID: 34285190
  • Shiying Xie, .et al. , Am J Physiol Renal Physiol, 2020, Aug 31 PMID: 32865015
  • Yang PM, .et al. , Am J Cancer Res, 2019, Oct 1;9(10):2120-2139 PMID: 31720078
  • Hui Fang, .et al. , Am J Physiol Cell Physiol, 2017, Dec 1; 313(6): C632-C643 PMID: 28903918
  • Tsutomu Nakagawa, .et al. , J Biochem, 2016, Apr 1;161(4):369-379 PMID: 28013223
  • Shimada S, .et al. , Virology, 2015, Aug;482:19-27 PMID: 25817401
  • Jan H. Reiling, .et al. , Nat Cell Biol., 2013, 15(12): 1473-1485 PMID: 24185178
  • Biological Activity
    Discription PF 429242 is a reversible, competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease.
    Product Information
    Catalog Num A11230
    Formula C25H35N3O2
    Molecular Weight 409.56
    CAS Number 947303-87-9
    SMILES CCN(CC)CC1=CC=C(C=C1)C(=O)N(CCC2=CC=CC=C2OC)[C@@H]3CCNC3
    Synonyms PF-429242, PF429242
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 77 mg/mL (188 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 24.42 mL 122.08 mL 244.16 mL
    0.5 mM 4.88 mL 24.42 mL 48.83 mL
    1 mM 2.44 mL 12.21 mL 24.42 mL
    5 mM 0.49 mL 2.44 mL 4.88 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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