PI3K/Akt/mTOR

Ispronicline is a neuronal nicotinic acetylcholine receptor partial agonist. Ispronicline is subtype-selective, binding primarily to the a4b2 subtype. It has antidepressant, nootropic and neuroprotective effects.

Nelonicline (ABT-126) is a selective neuronal nicotinic receptor agonist.

4BP-TQS is an allosteric agonist of α7 subunit-containing neuronal nicotinic acetylcholine receptors (nAChRs).

rac-BHFF is a selective GABAB receptor agonist.