Proteases

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  1. gamma-secretase modulator

    gamma-secretase modulator 3 is a gamma-secretase modulator.
  2. γ-secretase modulator

    BPN-15606 is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively.
  3. γ secretase modulator

    BI-1408 is a potent γ secretase modulator with an IC50 of 0.04 μM for Aβ42.

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