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PROTACs

PROTACs

Catalog No.

Product Name

Application

Product Information

Product Citation

A12517

PF-06282999

myeloperoxidase inhibitor

PF-06282999 is a potent and selective myeloperoxidase inhibitor which is potential useful for the treatment of cardiovascular diseases.

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A17062

AZD-5904

MPO inhibitor

AZD-5904 is a potent orally bioavailable MPO inhibitor. In preclinical studies, AZD-5904 inhibited the isolated MPO enzyme with an IC50 of 140 nM and was approximately equipotent in assays of rat and mouse MPO enzyme activity.

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