Protein Tyrosine Kinases

LM22A-4 is a potent tropomyosin-related kinase B (TrkB) agonist (IC50 = 47 nM).

7,8-Dihydroxyflavone, a selective tyrosine kinase receptor B (neurotrophic factor/tropomyosin-receptor-kinase B; TrkB) agonist, may be used to help identify and differentiate the physiological effects and cell signaling pathways mediated by TrkB activation, such as those involving neuroprotection, memory, vasorelaxation and hypertension.