ITK

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  1. ITK and RLK inhibitor

    PRN694 is a highly selective and potent covalent inhibitor of Tec kinases IL-2-inducible T cell kinase (ITK) and resting lymphocyte kinase (RLK). It inhibits Th1 and Th17 differentiation and cytokine production.
  2. ITK inhibitor

    GNE-4997 is a potent and selective ITK inhibitor with Ki value of 0.09 nM.

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