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Protein Tyrosine Kinases
TAM Receptor

TAM Receptor

Catalog No.

Product Name

Application

Product Information

Product Citation

A18523

UNC2541

Mer tyrosine kinase inhibitor

UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor, binds in the MerTK ATP pocket, with an IC50 of 4.4 nM, more selective over Axl, Tyro3 and Flt3. UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM).

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A22226

ONO-7475

Axl/Mer inhibitor

ONO-7475 is a potent, selective, and orally active Axl/Mer inhibitor with IC50 values of 0.7 nM and 1.0 nM, respectively.

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