β-catenin

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  1. Wnt/β-catenin signaling inhibitor

    IWP-4 is a novel potent inhibitor of Wnt/β-catenin signaling.
  2. Wnt/β-catenin signaling inhibitor

    DK419 is a potent and orally active Wnt/β-catenin signaling inhibitor, with an IC50 of 0.19 μM. DK419 reduces protein lelvels of Axin2, β-catenin, c-Myc, Cyclin D1 and Survivin and induces production of pAMPK.

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