Stem Cells/Wnt

TAK-441 is a pyrrolo[3,2-c]pyridine derivative, as a highly potent and orally active hedgehog signaling inhibitor.

LY-900009 is a potent inhibitor of Notch with IC50 value of 0.27 nM.

A 1070722 is a potent and selective glycogen synthase kinase 3 (GSK-3) inhibitor, with a Ki of 0.6 nM for both GSK-3α and GSK-3β.

GSK3 Inhibitor XIII (GSK3i XIII) is an ATP-binding site inhibitor of GSK-3.

BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor.