TRP Channel

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  1. TRPA1 activatior/TRPM8 blocker

    Cannabichromene is a major non-psychotropic phytocannabinoid that inhibits endocannabinoid inactivation and activates the transient receptor potential ankyrin-1 (TRPA1). Both endocannabinoids and TRPA1 may modulate gastrointestinal motility.
  2. TRPA1 agonist

    JT010 is a potent agonist of TRPA1 with an EC50 of 0.65 nM.
  3. TRPML3 ion channel activator

    SN 2 is a novel and potent activator of TRPML3 ion channel with EC50 of 1.8??0.13 μM.

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