Neurokinin Receptors

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  1. NK1 receptor antagonist

    NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective, specific and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50=2.6 nM) and in vivo.
  2. NK3R antagonist

    Pavinetant (MLE-4901) is a neurokinin-3 receptor (NK3R) antagonist.

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