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GPCR/G Protein
Smoothened Receptors

Smoothened Receptors

Catalog No.

Product Name

Application

Product Information

Product Citation

A18698

ALLO-2

Smo mutant antagonist

ALLO-2 is a potent drug-resistant Smoothened (Smo) mutant antagonist that inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.

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A21020

MRT-83

Smo antagonist

MRT-83 is a potent antagonist of Smo, with an IC50 in the nanomolar range. MRT-83 also blocks Hedgehog (Hh) signaling.

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