AMPA receptor

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  1. AMPA receptor modulator

    Farampator has been investigated for its effect on AMPA receptors and researched for potential use in the treatment of schizophrenia and Alzheimer's Disease. It was found to improve short-term memory, but impaired episodic memory.
  2. TARP γ-8 negative modulator

    AMPA Receptor Modulator-1 is a potent, oral active and selective AMPAR regulatory protein TARP γ-8 negative modulator with a pIC50 of 9.7, more selective over GluA1/γ-2 (pIC50=5).
  3. AMPAR negative modulator

    JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) γ-8, with a pIC50 of 9.7 for GluA1/γ-8.
  4. AMPA receptor modulator

    Org-26576 is a AMPA receptor positive allosteric modulator.
  5. AMPA receptor positive allosteric modulator

    PF-4778574 is a potent AMPA receptor positive allosteric modulator (PAM) that has been shown to enhance cognition in animal models.
  6. AMPA receptors allosteric modulator

    PEPA is an allosteric modulator of AMPA receptors; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity.
  7. AMPA receptors positive allosteric modulator

    CMPDA is a positive allosteric modulator of AMPA receptors with EC50s of 45.4 ?? 4.2 nM/63.4 ?? 5.6 nM for GluA2i/GluA2o receptor.
  8. positive AMPAR modulator

    CX546 is a selective positive AMPAR modulator; the prototypical ampakine agent.

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