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Apoptosis
Bcl-2 Family

Bcl-2 Family

Catalog No.

Product Name

Application

Product Information

Product Citation

A18378

dMCL1-2

MCL-1/PROTAC degrader

dMCL1-2 is a potent and selective degrader of myeloid cell leukemia 1 (MCL1) based on PROTAC, which binds to MCL1 with a KD of 30 nM. dMCL1-2 activats the cellular apoptosis machinery by degradation of MCL1.

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A22050

DT2216

BCL-XL degrader

DT2216 is a potent and selective BCL-XL degrader based on PROTAC technology.

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