LRRK2

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  1. LRRK2 inhibitor

    GNE-0877 is a highly potent and selective LRRK2 inhibitor.
  2. brain penetrant LRRK2 inhibitor

    MLi-2 is a potent, highly selective, orally available, brain penetrant inhibitor of LRRK2 with an IC50 of 0.76 nM.

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