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Metabolism

Metabolism

Catalog No.

Product Name

Application

Product Information

Product Citation

A20213

Voclosporin

calcineurin (CN) inhibitor

Voclosporin is a calcineurin (CN) inhibitor.

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A21424

MSI-1436

PTB1B inhibitor

MSI-1436 is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTB1B), with an IC50 of appr 1 μM, 200-fold preference over TCPTP (IC50, 224 μM).

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A21929

MSI-1436 lactate

PTB1B inhibitor

MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTB1B), with an IC50 of 1 μM, 200-fold preference over TCPTP (IC50 of 224 μM).

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