Catalog No.
Product Name
Application
Product Information
Product Citation
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Bcl-2 Family activator
(E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299. - (R)-Pantetheine is the biosynthetic precursor to CoA. (R)-Pantetheine and its corresponding disulfide pantethine, play a key role in metabolism as a building block of coenzyme A (CoA).
- β-cyano-L-Alanine (Beta-cyano-l-alanine), a nitrile of widespread occurrence in higher plants, is enzymatically produced by cyanoalanine synthase from cyanide and cysteine as substrates. β-cyano-L-Alanine abolishes the protective effect of ethanol on cerebral ischemia/reperfusion (I/R) injury.
- Taurodeoxycholate sodium salt is a bile salt-related anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) inhibits various inflammatory responses.
- Aminoadipic acid is an intermediate in the metabolism of lysine and saccharopine.
- 3b-Hydroxy-5-cholenoic acid is a monohydroxy bile acid of endogenous origin and could be found in children with the syndrome of hepatic ductular hypoplasia.
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cNIIIB nucleotidase inhibitor
7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor with IC50 value of 87.8????7.5??M. - 1-Methyladenine is a product of alkylation damage in DNA which can be repaired by damage reversal by oxidative demethylation.
- (S)-3,4-Dihydroxybutyric acid is a normal human urinary metabolite that is excreted in increased concentration in patients with succinic semialdehyde dehydrogenase (SSADH) deficiency.
- Hexacosanoic acid is a long-chain fatty acid related to various diseases such as adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis.
- 4-Guanidinobutanoic acid is a normal metabolite present in low concentrations.
- 7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3.
- Leucyl-phenylalanine belongs to the class of organic compounds known as dipeptides.
- Valerylcarnitine is an endogenous metabolite, belonging to the short-chain acylcarnitines.
- 8-Hydroxyguanosine is a systematic marker of oxidative stress and a marker of hydroxyl radical damage to RNA.
- 2-Methoxyestrone is a methoxylated catechol estrogen and metabolite of estrone, with a pKa of 10.81.
- 3-Nitro-L-tyrosine is a biomarker of nitrogen free radical species modified proteins in systemic autoimmunogenic conditions.
- trans-trans-Muconic acid is a urinary metabolite of benzene and has been used as a biomarker of exposure to benzene in human.
- p-Synephrine is an organic compound, found in multiple biofluids, such as urine and blood.
- Oxoadipic acid is a key metabolite of the essential amino acids tryptophan and lysine.
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Calpain activator
Isovalerylcarnitine is a product of the catabolism of L-leucine. It increases calpain activity. - Tetradecanoylcarnitine is a human carnitine involved in β-oxidation of long-chain fatty acids.
- Butyrylcarnitine is a metabolite in plasma, acts as a biomarker to improve the diagnosis and prognosis of heart failure, and is indicative of anomalous lipid and energy metabolism.
- Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease.
- Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases. Isobutyryl-L-carnitine is a member of the class of compounds known as acyl carnitines.
- Bovinic acid is a conjugated linoleic acid with anticarcinogenic and anti-atherogenic activities.
- L-Octanoylcarnitine is the physiologically active form of octanoylcarnitine.
- Docosapentaenoic acid (22n-3) is a component of phospholipids found in all animal cell membranes.
- L-Hexanoylcarnitine is an acylcarnitine and is found to be associated with celiac disease.
- Galactose 1-phosphate is an intermediate in the galactose metabolism and nucleotide sugars.
- 1-Methylinosine is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA.
- 3-Methyluridine is a modified nucleoside of cellular RNA.
- Gefei Huang, .et al. , Talanta, 2023, Oct 1;263:124697 PMID: 37262985
- N2,N2-Dimethylguanosine is an urinary nucleoside, a primary degradation product of tRNA.
- Dihydroxyacetone phosphate is an important intermediate in lipid biosynthesis and in glycolysis. It is a biochemical compound involved in many metabolic pathways, including the Calvin cycle in plants and glycolysis.
- Eicosadienoic acid is a rare, naturally occurring n-6 polyunsaturated fatty acid found mainly in animal tissues.
- Glycerol 3-phosphate is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis.
- (S)-3-Hydroxyisobutyric acid is an important interorgan metabolite, an intermediate in the pathways of l-valine and thymine and a good gluconeogenic substrate.