Glucosidase

Afegostat D-tartrate was an experimental drug for the treatment of certain forms of Gaucher's disease. The substance was used in form of the tartrate. Isofagomine (IFG) is an acid β-glucosidase (GCase) active site inhibitor that acts as a pharmacological chaperone.

Licochalcone C was synthesized from commercially available 2,4-dihydroxybenzaldehde by using regioselective Al2O3-mediated C-prenylation followed by conventional Claisen-Schmidt condensation in basic condition.

ML198 is a novel activator and non-inhibitory chaperone of glucocerebrosidase.

NCGC607 is a a noninhibitory chaperone of glucocerebrosidase (GCase).