Metabolism - SRPK

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  1. SRPK inhibitor

    SRPIN340 is a cell-permeable isonicotinamide that acts as an ATP-competitive SRPK1-selective inhibitor (IC50 = 0.14 and 1.8 μM, respectively, against mSRPK1 and mSRPK2) with much reduced activity against 143 other kinases.
  2. Serine/arginin kinase 1 inhibitor

    SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50 = 5.9 nM).

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