Mitochondrial Metabolism

Oligomycin A is a mitochondrial ATPase inhibitor. Oligomycin A inhibits ATP5 (mitochondrial ATPases, F1F0) bound to the cell membrane.

Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate is a potent and irreversible inhibitor of mitochondrial respiratory chain.

Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Gboxin inhibits the activity of F0F1 ATP synthase. Antitumour activity.

AC-5216 is a translocator protein [TSPO (18 kDa)] ligand.

iMAC2 inhibits mitochondrial apoptosis-induced channel (MAC) (IC50 = 28 nM).

KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL-1333 Improves Energy Metabolism and Mitochondrial Dysfunction in MELAS Fibroblasts.

BI-6C9 is a BH3 interacting domain (Bid) inhibitor, which prevents mitochondrial outer membrane potential (MOMP) and mitochondrial fission, and protects the cells from cell death.

Fumarate hydratase-IN-1 (compound 2) is a cell-permeable fumarate hydratase inhibitor. Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2.2 μM.

Mitochondrial Ribosomal Protein L13 Human Recombinant

Mitochondrial RRNA Methyltransferase 1 Human Recombinant

5',3'-Nucleotidase, Mitochondrial Human Recombinant

Mitochondrial Trans-2-Enoyl-CoA Reductase Human Recombinant

3-Oxoacyl-ACP Synthase, Mitochondrial Human Recombinant