Sivelestat
Important Notice: For research use only. We do not sell to patients.
Other Forms of Sivelestat
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | Sivelestat is a cell-permeable sulfanilide compound that acts as a potent, substrate-competitive, and highly specific inhibitor of neutrophil elastase (IC50 = 19-49 nM in rat, rabbit, hamster, human, and mouse leukocyte elastase). | ||
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Catalog Num | A14184 |
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Formula | C20H22N2O7S |
Molecular Weight | 434.46 |
CAS Number | 127373-66-4 |
SMILES | CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)O |
Synonyms | Elastase Inhibitor IV |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 76 mg/mL (174.92 mM) | |
Water | Insoluble | ||
Ethanol | 76 mg/mL (174.92 mM) | ||
In vivo | 5% DMSO+40% PEG 300+5% Tween 80+ddH2O | 21 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 23.02 mL | 115.09 mL | 230.17 mL |
0.5 mM | 4.6 mL | 23.02 mL | 46.03 mL |
1 mM | 2.3 mL | 11.51 mL | 23.02 mL |
5 mM | 0.46 mL | 2.3 mL | 4.6 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2