IRE1

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  1. IRE-1 RNase inhibitor

    B I09 is an IRE-1 RNase inhibitor, with an IC50 of 1230 nM.
  2. IRE1α inhibitor

    Kira8 Hydrochloride (AMG-18 Hydrochloride) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.

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