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DNA Damage
Topoisomerase

Topoisomerase

Catalog No.

Product Name

Application

Product Information

Product Citation

A13656

Belotecan (CKD602 free base)

Topoisomerase I inhibitor

CKD-602 is a topoisomerase I inhibitor.

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A13993

NK314

Topoisomerase II inhibitor

NK314 is a novel synthetic benzo[c]phenanthridine alkaloid that shows strong antitumor activity. It inhibited topoisomerase II activity and stabilized topoisomerase II-DNA cleavable complexes.

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- Kopa P, .et al. , Mol Biol Rep, 2019, Oct 3 PMID: 31583565
- Macieja A, .et al. , Mol Biol Rep, 2019, Apr 24 PMID: 31020489
A15467

Clorobiocin

DNA Gyrase Inhibitor

Clorobiocin is an aminocoumarin.

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A21146

Namitecan

topoisomerase I inhibitor

Namitecan is a potent topoisomerase I inhibitor, with antitumor property.

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A22471

Topovale

topoisomerase I inhibitor

Topovale, also known as ARC-111, is a potent topoisomerase I inhibitor.

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