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DNA Damage
Topoisomerase

Topoisomerase

Catalog No.

Product Name

Application

Product Information

Product Citation

A21156

Karenitecin

topoisomerase I inhibitor

Karenitecin (Cositecan) is a topoisomerase I inhibitor, with potent anti-cancer activity.

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A21517

Dxd

DNA topoisomerase I inhibitor

Dxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).

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