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Topoisomerase

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  1. A11231
    Exatecan

    Topoisomerase I inhibitor

    Exatecan inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death.
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    $600.00 - $700.00
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