Androgen Receptors

GSK-2881078 is a selective androgen receptor modulator (SARM) that is being evaluated for effects on muscle growth and strength in subjects with muscle wasting to improve their physical function.

LGD-4033 is an investigational selective androgen receptor modulator for treatment of conditions such as muscle wasting and osteoporosis, currently under development by Ligand Pharmaceuticals.

LY2452473 is an orally bioavailable selective androgen receptor modulator (SARM), with potential tissue-selective androgenic/anti-androgenic activity.

RAD140 is a potent, orally bioavailable, nonsteroidal selective androgen receptor modulator (SARM).

S-23 is an orally active selective androgen receptor modulator (SARM) with a Ki of 1.7 nM.